Title of article :
An Efficient and Selective End-Modification of High-Molecular Weight Poly(Ethylene Glycol)s
Author/Authors :
Campaner, Pietro University of Trieste - Department of Chemical Science, Italy , Bonora, Gian Maria University of Trieste - Department of Chemical Science, Italy , Drioli, Sara University of Trieste - Department of Chemical Science, Italy
Abstract :
An innovative procedure aimed to the production of orthogonally protected amino-derivatives of high-molecular weight poly(ethylene glycol) (PEG) modified with linkers bearing differently reactive terminalamino groups is reported. This polymeric derivative represents a convenient, new soluble support particularly suitable as a drug delivery system of mixed molecules.
Keywords :
Poly(ethylene glycol) , PEG , polymer , conjugates , peptide , drug delivery
Journal title :
letters in organic chemistry
Journal title :
letters in organic chemistry
