Title of article
Novel One-Pot Synthesis of Amide Derivatives of Methylenebisphosphonate Utilizing the Mesyl Moiety as Leaving Group
Author/Authors
Jokiniemi, Jonna University of Joensuu - Department of Chemistry, Finland , Ahlgrén, Markku University of Joensuu - Department of Chemistry, Finland , Vepsäläinen, Jouko J. University of Kuopio - Department of Chemistry, Finland
From page
898
To page
900
Abstract
A novel one-pot synthesis was developed for the preparation of partial amide esters of(dichloromethylene)bisphosphonic acid from readily available tetramethyl ester with good selectivity and purity.
Keywords
Bisphosphonate , amide esters , selective synthesis , mesyl leaving group , amination
Journal title
letters in organic chemistry
Journal title
letters in organic chemistry
Record number
2718109
Link To Document