Author/Authors :
Nasiri, Mona Department of Pediatrics - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Azarfar, Anoush Kidney Transplantation Complication Research Center - Mashhad University of Medical Sciences, Mashhad, Iran , Ravanshad, Yalda Department of Community Medicine - Islamic Azad University Mashhad Branch, Mashhad, Iran , Saberafsharian, Malihe Islamic Azad University Mashhad Branch, Mashhad, Iran , Kaboli, Sepide Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
A 13-year-old girl was admitted to our hospital because of fatigue, oliguria, and edema of lower extremities. Her laboratory workup showed an acute renal failure (BUN= 225 mg/dl, Creatinine= 13.25 mg/dl). She also had a massive proteinuria. A renal biopsy showed cellular crescentic glomerulonephritis and positive C-ANCA. The serum Creatinine level decreased after dialysis and treatment with high-dose methylprednisolone, rituximab and plasmapheresis. She did not require dialysis after discharge from the hospital. This is a report of a rare case of GPA presenting with 100% cellular crescentic glomerulonephritis.
Keywords :
Pauci-Immune Necrotizing Glomerulonephritis , Crescentic Glomerulonephritis , Wegener's Granulomatosis , Child
