Author/Authors :
PARVEEN, SHAHIDA King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan , BUKHARI, M. H. King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan , KHAN, S. AKHTAR King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan , NAVEED, I. A King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan , CHAUDHRY, N. A. King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan , TAHSEEN, M. King Edward Medical College - Mayo Hospital - Department of Pathology, Pakistan
Abstract :
In this era of tumour marker AgNOR stain has still retained the diagnostic yield in tumour pathology. This study was conducted to evaluate the role of AgNOR number and morphological features in cirrhotic and carcinomatous liver. A total of one hundred liver biopsy specimens were included, twenty cases were of hepatocellular carcinoma, sixty were those of cirrhosis of the liver and twenty cases with normal histology as control. The mean AgNOR count, size and distribution were significantly of higher grade in hepatocellular carcinoma as compared to cirrhosis of liver
