A COMPARISON OF THE EFFECTS OF GAMMA GLUTAMYLTRANSFERASE ON AGE AND OBESITY AMONG NORMAL, HYPERTENSIVE AND TYPE 2 DIABETICS

The purpose of this work was to compare the effects of Gamma Glutamyltransferase on age and obesity among normal, hypertensive and type 2 diabetics. It is a cross-sectional study which was conducted in the department of Physiology B.M.S.I., J.P.M.C. Karachi from December 2006 to October 2007. All subjects who have never used alcohol in their lifetime were selected. A total of 100 normal, 50 each diabetic and hypertensive patients were recruited to the study. Increase in age was significantly associated with raised GGT levels in normal, hypertensive and type 2 diabetic subjects (p 0.01). GGT levels were significantly (p 0.001) greater in both hypertensive and diabetic subjects compared to normal subjects. The study confirms the relation between age obesity with GGT levels among non-alcoholics. This study also indicates the significance of GGT among diabetics and hypertensive patients.