Title of article :
Evaluation of Serum Cyclooxygenase, Hepcidin Levels in Acute Renal Injury (AKI) Patients Following Cardiac Catheterization
Author/Authors :
Fawzi Aref, Hind Department of Chemistry - College of Science - University of Baghdad, Baghdad 10013, Iraq , Naji, Nazar Ahmed Department of Chemistry - College of Science - University of Tikrit - Salah Al Deen 34001, Iraq , Dhafir Ibrahim, Hadaf Department of Clinical Biochemistry - College of Medicine - University of Baghdad, Baghdad 10013, Iraq
Abstract :
Background: Acute kidney damage is a severe condition common in patients who have undergone heart surgery (catheterization) and secondary injury is also referred to as being synonymous with surgery. The goal of this research is to determine the rate of cyclooxygenase and hepcidin levels in patients with acute renal injury (AKI) following cardiac catheterization.
Methods: The study is performed on (81) patients (64 males and 17 females) aged 40-75 years. Data from most
patients are reported in the form of age, gender, and smoking background questionnaire.
Results: The results indicate a significant increase in serum levels of cyclooxygenase and hepcidin
levels in patients with severe renal insufficiency after cardiac catheterization by (79%) males versus
(21%) females.
Conclusions: In this study, improved risk prediction could enhance patient monitoring and treatment after
surgery, direct patient treatment and decision making, and enhance participation in AKI interventional trials.
Keywords :
AKI , Cardiac surgery , Chronic kidney disease , Cyclooxygenase , Hepcidin
Journal title :
Reports of Biochemistry and Molecular Biology (RBMB)