Clinical and radiographic evaluation of platelet-rich fibrin as a pulpotomy agent in primary molars

Objective This study was carried out to evaluate clinical and radiographic effect of platelet‑rich fibrin (PRF) as a pulpotomy agent in primary molars. Patients and methods In this randomized‑controlled clinical trial, 20 children aged from 4 to 8 years old, each one had at least two lower primary carious molars. Forty selected molars were assigned randomly to one of the two treatment groups: group I (study group): the pulp treated using PRF. Group II (positive control group): the pulp treated using formocresol (FC). All pulpotomized teeth were restored with preformed stainless steel crowns. Then all the patients were evaluated every 3 months over a period of 12 months with clinical and radiographic examination. Results At the end of this study, the clinical success rate of the PRF group showed 89.5%, whereas FC group showed 94.7%. In contrast, the radiographic success results of the PRF group showed (78.9%), whereas FC group displayed success rate of 84.1%. There was no statistically significant differences between the two groups regarding to their clinical performance (P = 0.547) and radiographic performance (P = 0.676). Conclusion PRF is considered an acceptable pulpotomy agent that can be used as an alternative to FC.