The impact of β‑thalassemia major on dental maturity in children at different stages of dental development (In TDJ, we do not quey for manuf details)

Purpose Assess the dental maturity in B thalassemic children at different stages of dental development. Patients and methods Fifty‑four β‑thalassemia patients were enrolled and classified into: group Іa, 16 patients with age range 3–6 years; group Іb, 18 patients with age 6–12 years; and group Іc, 20 patients older than 12 years. Another 25 healthy children were enrolled as controls. All involved children were subjected to clinical examination stressing on the anthropometric measures, complete blood count, serum ferritin, and oral panoramic radiograph to assess the dental age which is plotted on the charts to assess the dental age centile and dental maturity score. Results Significant differences were found between patients and control regarding serum ferritin (P = 0.001), hemoglobin level (P = 0.001), height (P = 0. 001), BMI (P = 0.009), dental age centile (P = 0.02). Dental age was positively correlated with age (P = 0.001, r = 0.9) and serum ferritin level (P = 0.009, r = 0.4). Dental age centile was negatively correlated with age (P = 0.001, r=−0.5) and serum ferritin level (P = 0.001, r=−0.6). Dental maturity score was positively correlated with age (P = 0.001, r = 0.9), age of start transfusion (P = 0.008, r = 0.4) and serum ferritin level (P = 0.002, r = 0.4).