Author/Authors :
Chuang, Y.W Department of Nuclear Medicine - Kaohsiung Medical University Hospital - Kaohsiung, Taiwan , Lin, C.Y Department of Nuclear Medicine - Kaohsiung Medical University Hospital - Kaohsiung, Taiwan , Hsu, C.C Department of Nuclear Medicine - Kaohsiung Chang Gung Memorial Hospital - Chang Gung University College of Medicine, Taiwan , Huang, Y.F Department of Medical Imaging and Radiological Sciences - College of Health Science - Kaohsiung Medical University, Kaohsiung, Taiwan , Chang, C.C School of Medicine - Kaohsiung Medical University, Kaohsiung, Taiwan - Department of Nuclear Medicine - Kaohsiung Medical University Hospital - Kaohsiung, Taiwan , Ho, S.Y Department of Radiation Oncology - Chi Mei Medical Center - Tainan, Taiwan - Graduate Institute of Medical Science - Chang Jung Christian University, Tainan, Taiwan , Tyan, Y.C Center for Cancer Research - Kaohsiung Medical University, Kaohsiung, Taiwan - Department of Medical Imaging and Radiological Sciences - College of Health Science - Kaohsiung Medical University, Kaohsiung, Taiwan
Abstract :
Background: Fibrous dysplasia is a rare benign bone disorder characterized by the fibrous tissue containing trabeculae of non-lamellar bone (woven bone) and occupying normal medullary spaces. The uptake of the radiotracer in the affected bone is variable, and specificity is too low to diagnose fibrous
dysplasia in the bone scan. Materials and Methods: We are presenting four
cases with monostotic fibrous dysplasia which were detected incidentally on
the routine planar bone scan while being investigated for a metastatic cancer
work-up. During a cancer work-up at our institution, we find lesions of fibrous
dysplasia showing significantly increased uptake on the bone scan which may
mimic metastatic bone lesions. Results: The SPECT/CT increases diagnostic
confidence and improves accuracy and specificity of a planar bone scan.
These cases were all asymptomatic at the one-year follow-up The subsequent
bone scan and radiography studies have revealed no progression of these
bone lesions. Conclusion: The SPECT/CT images increase the diagnostic
accuracy of the bone scan, which may avoid unnecessary surgery or
overtreatment of fibrous dysplasia as bone metastasis. Abbreviation: SPECT/ CT = single photon emission computed tomography/computed tomography.
Keywords :
Bone scan , bone metastasis , fibrous dysplasia , SPECT/CT
