Author/Authors :
Bananzadeh, Alimohammad Colorectal Research Center - Shiraz University of Medical Sciences - Shiraz, Iran , Vahidi, Abtin Colorectal Research Center - Shiraz University of Medical Sciences - Shiraz, Iran , Salahi, Sarvenaz Minimally Invasive Surgery Research Center - Iran University of Medical Sciences - Tehran, Iran , Foroutan, Ali Burn and Wound Healing Research Centre - Shiraz University of Medical Sciences - Shiraz, Iran , Ghahramani, Leila Colorectal Research Center - Shiraz University of Medical Sciences - Shiraz, Iran
Abstract :
To evaluate the role of heart rate variability (HRV) in predicting pre-operative severity of
appendicitis.
Methods: In this cross-sectional study, 171 cases of acute appendicitis who underwent appendectomy were
enrolled. Pre-anesthetic pulse rate of included patients were documented while the severity of appendicitis was
determined by intra-operative evidences reported by two independent surgeons. Demographic characteristics,
laboratory variables, and Alvarado criteria were recorded.
Results: The mean age of patients was 28.75±4.21 years; 54% were men. HRV negatively associated the
severity of appendix inflammation. A positive association was found between HRV and omental wrapping and
Alvarado score (p<0.01). The receiver operating characteristic (ROC) curve analysis demonstrated that HRV
could differentiate simple and complicated appendicitis with a sensitivity of 78.5% and specificity of 97.2%.
Conclusion: The present findings revealed that HRV may predict the pre-operative severity of appendicitis and
help differentiate simple and complicated appendicitis.
Keywords :
Appendicitis , Heart rate variability , Medication therapy management , Cross-sectional study
