Title of article :
Rabies Infection: An Overview of Lyssavirus-Host Protein Interactions
Author/Authors :
Zandi ، Fatemeh Medical Biotechnology Department - Biotechnology Research Center - Pasteur Institute of Iran , Goshadrou ، Fatemeh Department of Basic Sciences - Faculty of Paramedical Sciences - Shahid Beheshti University of Medical Sciences , Meyfour ، Anna Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences , Vaziri ، Behrouz Medical Biotechnology Department - Biotechnology Research Center - Pasteur Institute of Iran
Abstract :
Viruses are obligatory intracellular parasites that use cell proteins to take the control of the cell functions in order to accomplish their life cycle. Studying the viral-host interactions would increase our knowledge of the viral biology and mechanisms of pathogenesis. Studies on pathogenesis mechanisms of lyssaviruses, which are the causative agents of rabies, have revealed some important host protein partners for viral proteins, especially for most studied species, i.e. RABV. In this review article, the key physical lyssavirus-host protein interactions, their contributions to rabies infection, and their exploitation are discussed to improve the knowledge about rabies pathogenesis. DOI: 10.52547/ibj.25.4.226
Keywords :
Host , Pathogen Interactions , Lyssavirus , Rabies
Journal title :
Iranian Biomedical Journal(IBJ)
Journal title :
Iranian Biomedical Journal(IBJ)
