Title of article :
Testosterone Improved Hyperalgesia in a Patient Under Methadone Maintenance Treatment
Author/Authors :
Charkhgard ، Nader Department of Neuroscience and Addiction Studies - School of Advanced Technologies in Medicine - Tehran University of Medical Sciences , Naderi ، Shahram Department of Neuroscience and Addiction Studies - School of Advanced Technologies in Medicine - Tehran University of Medical Sciences , Ghani ، Kamyar Department of Neuroscience and Addiction Studies - School of Advanced Technologies in Medicine - Tehran University of Medical Sciences , Manouchehrabadi ، Mahboubeh Department of Neuroscience and Addiction Studies - School of Advanced Technologies in Medicine - Tehran University of Medical Sciences
Abstract :
Introduction: Long-term use of narcotics causes hyperalgesia in some patients with an unknown mechanism known as opioidinduced hyperalgesia (OIH). Case Presentation: Testosterone was prescribed to a 43-year-old man suffering from the effects of OIH syndrome due to long-term use of methadone. Testosterone prescription significantly reduced the hyperalgesia. Conclusions: Testosterone may have a therapeutic value in OIH.
Keywords :
Opioid , Hyperalgesia , Testosterone
Journal title :
Archives of Neuroscience
Journal title :
Archives of Neuroscience
