Author/Authors :
Sadabadi ، Fatemeh Cutaneous Leishmaniasis Research Center, Metabolic Syndrome Research Center, Faculty of Medicine - Mashhad University of Medical Sciences , Asadi ، Zahra Metabolic Syndrome Research Center, Faculty of Medicine - Mashhad University of Medical Sciences , Heidari Bakavoli ، Alireza Cardiovascular Research Center, Faculty of Medicine - Mashhad University of Medical Sciences , Darroudi ، Susan International UNESCO Center for Health-Related Basic Sciences and Human Nutrition - Mashhad University of Medical Sciences , Saberi-Karimian ، Maryam International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Lung Diseases Research Center - Mashhad University of Medical Sciences , Saljoughian ، Saniya Metabolic Syndrome Research Center, Faculty of Medicine - Mashhad University of Medical Sciences , Shahi ، Maryam Blood Borne Infections Research Center - Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch , Safarian ، Mohammad Department of Nutrition - Faculty of Medicine - Mashhad University of Medical Sciences , Nematy ، Mohsen Department of Nutrition - Faculty of Medicine - Mashhad University of Medical Sciences , Ferns ، Gordon Department of Medical Education - Brighton Sussex Medical School , Ghayour Mobarhan ، Majid Metabolic Syndrome Research Center, Faculty of Medicine, International UNESCO Center for Health-Related Basic Sciences and Human Nutrition,Cardiovascular Research Center - Mashhad University of Medical Sciences , Mouhebati ، Mohsen Cardiovascular Research Center, Faculty of Medicine - Mashhad University of Medical Sciences
Abstract :
Introduction: The association between the serum antibody titer of several heat shock proteins (HSPs) and cardiovascular disease (CVD) risk factors so far has been the subject of several previous studies . Aim: To evaluate the association of adiposity indices and HSP-27 antibody titers in healthy individuals. Materials and Methods: Overall 4823 individuals were recruited from Mashhad Stroke and Heart Atherosclerotic Disorders Study (MASHAD study), that included 1496 individuals with normal-weight (body mass index (BMI) 25 kg/m2), 1975 individuals with over-weight (BMI 25-30 kg/m2), and 1352 individuals with obesity (BMI≥ 30 kg/m2). Results: The serum anti-HSP-27 antibody titers were not significantly different among obese individuals [0.21 (0.11 – 0.34) absorbency unit (AU)], over-weight individuals [0.19 (0.10 – 0.33) AU] and normal-weight individuals [0.19 (0.10 – 0.33) AU]. Conclusions: we have found no significant relationship among anti-HSP-27 antibody concentration and degrees of adiposity among Iranian adults.
