Author/Authors :
Jafari, Nahid Department of Neonatology and Perinatology - Zanjan University of Medical Science, Zanjan, Iran , Karimi Moghadam, Arezoo Zanjan University of Medical Science, Zanjan, Iran , Taslimi Taleghani, Naeeme Neonatal Health Research Center - Research Institute for Children’s Health - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Hosseini Nezhad, Neda Department of Pediatrics - Zanjan University of Medical Science, Zanjan, Iran , Motamed, Nima Department of Social Medicine - Medical School - Zanjan university of Medical Science, Zanjan, Iran , Jalilvand, Ahmad Department of Pathology - Zanjan University of Medical Science, Zanjan, Iran
Abstract :
Background: Evaluation of insulin‑like growth factor‑1 (IGF‑1) association with retinopathy of prematurity (ROP) is our object.
Materials and Methods: This study was conducted on IGF‑1 levels of 40 neonates <34 weeks gestational age and 2000 g at 1st week
and 4–6 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation. Results: IGF‑1 levels showed a
significant difference between neonates ≤1500 and 1500–2000 g (1 and 4–6 weeks, P = 0.008, P = 0.039, respectively). No significant
association was found between IGF‑1 and ROP. Conclusion: Finding a meaningful association between IGF‑1 and ROP requires
consideration of factors affecting the IGF‑1.
