synthesis and characterization of new thiazolidinone and oxazolidinone heterocyclic derivatives from 2-marcapto-1,3,4-thiadiazole compounds

the previous effort involved the synthesis of unprecedented schiff s bases compounds of hydrazine hydrate linked with ethyl 4-hydroxybenzoate, which in turn reacted with carbon disulfide (cs2) and potassium hydroxide (koh) as catalyst to synthesize 2-marcapto-1,3,4-thiadiazole which reacts with methyl bromoacetate in the presence of triethyl amine n(ch2ch3)3 to form an ester whose methoxy group is converted into a hydrazide, and then reacts with different aromatic aldehydes to form schiff bases, from which the thiazolidinone and oxazolidinonefive-membered ring heterocyclic compounds derivatives were formed. all synthetic substances have high yields. the melting points of all compounds and some of their 1h-nmr and ft-ir spectra, were used to authenticate their identities.