Title of article
Synthesis, Examination of Various Seven Rings, and Effects on Corrosion and Fungus
Author/Authors
Jarallah ، Aziz Latif Department of Medical Labs. Techniques - Al-Esraa University College , Kareem ، Aseel Fadhil College of Pharmacy - University of Babylon
From page
532
To page
539
Abstract
The majority of benzodiazepines is administered orally and has various beneficial effects, including psychotropic, anxiolytic, hypnotic, sedative, muscle relaxing, anticonvulsant, and amnesic ones. These include benefits for alcohol dependence, epileptic seizures, irritable disorders, scare, and insomnia. The goal of this study was to create bicycles from benzodiazepines through cyclization steps. All generated compounds were examined by using several analytical techniques, including: FT-IR, 1H-NMR, Mass spectroscopy analysis, and other chemical characterization, with formatted compounds being assessed as antifungals and inhibitors. These compounds were utilized to explain biological activity against Aspergilla s and Candida albicans at various concentrations (5, 10, 15, and 20 mg/ml-1). The findings demonstrated that all compounds were active against all varieties of fungi and that oxazepine, diazepine bicycles, and heteroatoms in the structure inhibited the corrosion of mild steel in 0.5M HCl.
Keywords
Cycloaddition reaction , Oxazepine , Diazepine , corrosion , Schiff bases , Antifungal activity
Journal title
Journal of Medicinal and Chemical Sciences
Journal title
Journal of Medicinal and Chemical Sciences
Record number
2728185
Link To Document