Title of article :
Synthesis, Examination of Various Seven Rings, and Effects on Corrosion and Fungus
Author/Authors :
Jarallah ، Aziz Latif Department of Medical Labs. Techniques - Al-Esraa University College , Kareem ، Aseel Fadhil College of Pharmacy - University of Babylon
From page :
532
To page :
539
Abstract :
The majority of benzodiazepines is administered orally and has various beneficial effects, including psychotropic, anxiolytic, hypnotic, sedative, muscle relaxing, anticonvulsant, and amnesic ones. These include benefits for alcohol dependence, epileptic seizures, irritable disorders, scare, and insomnia. The goal of this study was to create bicycles from benzodiazepines through cyclization steps. All generated compounds were examined by using several analytical techniques, including: FT-IR, 1H-NMR, Mass spectroscopy analysis, and other chemical characterization, with formatted compounds being assessed as antifungals and inhibitors. These compounds were utilized to explain biological activity against Aspergilla s and Candida albicans at various concentrations (5, 10, 15, and 20 mg/ml-1). The findings demonstrated that all compounds were active against all varieties of fungi and that oxazepine, diazepine bicycles, and heteroatoms in the structure inhibited the corrosion of mild steel in 0.5M HCl.
Keywords :
Cycloaddition reaction , Oxazepine , Diazepine , corrosion , Schiff bases , Antifungal activity
Journal title :
Journal of Medicinal and Chemical Sciences
Journal title :
Journal of Medicinal and Chemical Sciences
Record number :
2728185
Link To Document :
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