Author/Authors :
mailafiya, mm gombe state university - department of pharmaceutical and medicinal chemistry, department of pharmacognosy and drug development, Gombe, Nigeria , pateh, uu ahmadu bello university - department of pharmaceutical and medicinal chemistry, Zaria, Nigeria , hassan, hs ahmadu bello university - department of pharmaceutical and medicinal chemistry, Zaria, Nigeria , sule, mi ahmadu bello university - department of pharmaceutical and medicinal chemistry, Zaria, Nigeria , bila, ah ahmadu bello university - department of pharmaceutical and medicinal chemistry, Zaria, Nigeria , musa, tl gombe state university - department of pharmaceutical and medicinal chemistry, department of pharmacognosy and drug development, Gombe, Nigeria , atinga, v gombe state university - department of pharmaceutical and medicinal chemistry, department of pharmacognosy and drug development, Gombe, Nigeria , achika, ji federal university lokoja - department of chemistry, Lokoja, Nigeria
Abstract :
Dried stem bark powder of Leptadania hastata was subjected to maceration with methanol to afford crude methanol extract, which was partitioned with n-hexane, ethylacetate, chloroform and n- butanol to afford different their respective fractions. Extensive phytochemical screening of the n-hexane fraction using column chromatography resulted to the isolation of a white solid substance. The substance was identified as of lupeol using IR, 1D – NMR, 2D – NMR data and by comparison with reference spectral data.
Keywords :
Leptadenia hastata , Isolation , Lupeol , 1D – NMR , 2D – NMR
