Author/Authors :
Mousa, F. A Department of Microbiology - College of Medicine - University of Basrah, Basrah, Iraq , Jasim, H. A Department of Microbiology - College of Medicine - University of Basrah, Basrah, Iraq , Shakir, F Department of Surgery - College of Medicine - University of Basrah, Basrah, Iraq
Abstract :
Urinary bladder cancer is a worldwide health issue and the ninth most prevalent cancer across the globe,
accounting for almost two-thirds of all urinary malignancies. Interleukin 17 (IL17) is a pro-inflammatory
cytokine with pivotal modulatory effects on antitumor immune responses and has been reported to play a
prominent role in the occurrence and development of bladder cancer. The present study aimed to measure the
quantitative serum and urine levels of IL-17 in patients with bladder cancer. Blood and urine samples were
obtained from 50 diagnosed bladder cancers and 96 healthy people as a control group. The serum and urine
level of IL-17 was evaluated using an enzyme-linked immunosorbent assay. It has been revealed that the level of IL-17 was higher in all patients, as compared to that in controls. These results indicated that this interleukin is an indicator to predict the progression or recurrence of the disease.
