Author/Authors :
Masoumi, Maryam Clinical Research and Development Center - Qom University of Medical Sciences - Qom, Iran , Sharifi, Alireza Clinical Research and Development Center - Qom University of Medical Sciences - Qom, Iran , Rezaei, Sepideh School of Health Management and Information Sciences - Iran University of Medical Sciences - Tehran, Iran , Rafiei, Sima Social Determinants of Health Research Center - Research Institute for Prevention of Non-Communicable Diseases - Qazvin University of Medical Sciences - Qazvin, Iran , Hosseinifard, Hossein Research Center for Evidence-Based Medicine - Tabriz University of Medical Sciences - Tabriz, Iran , Khani, Saghar School of Medicine - Iran University of Medical Sciences - Tehran, Iran , Doustmehraban, Maryam Social Determinants of Health Research Center - Research Institute for Prevention of Non-Communicable Diseases - Qazvin University of Medical Sciences - Qazvin, Iran , Rajabi, Mona Social Determinants of Health Research Center - Research Institute for Prevention of Non-Communicable Diseases - Qazvin University of Medical Sciences - Qazvin, Iran , Beiramy Chomalou, Zahra Student Research Committee - School of Nursing and Midwifery - Iran University of Medical Sciences - Tehran, Iran , Soori, Parisa Student Research Committee - School of Nursing and Midwifery - Iran University of Medical Sciences - Tehran, Iran , Javan Biparva, Akbar Student Research Committee - School of Health Management and Medical Informatics - Iranian Center of Excellence in Health Management - Tabriz University of Medical Sciences - Tabriz, Iran. , Dehnad, Afsaneh School of Health Management and Information Sciences - Center for Educational Research in Medical Sciences (CERMS) - Iran University of Medical Sciences - Tehran, Iran , Pashazadeh kan, Fatemeh Student Research Committee - School of Nursing and Midwifery - Iran University of Medical Sciences - Tehran, Iran , Ghashghaee, Ahmad Student Research Committee - Qazvin University of Medical Sciences - Qazvin, Iran
Abstract :
Background: Behcet’s disease is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s disease.
Methods: A total of 13 articles were extracted from four main databases including PubMed, EMBASE, Scopus, and Web of Science from the onset of 2000 to January 2021. All studies published in English with the purpose of examining quality of life (QOL) among patients with BD or investigating its main determinants were included.
Results: Totally, 1137 BD patients participated in 13 studies. Based on random effect analysis, the total score of physical health-related QOL was 46.7 (95% CI=41.26 to 52.13) and the total score of mental health-related QOL was 49.01 (95% CI=43.83 to 54.18) representing a moderate level of QOL among BD patients. Furthermore, weighted effect size analyses showed a significant correlation between QOL and variables such as patients’ age, gender, disease duration and depression (pvalue: 0.00).
Conclusion: As the symptoms of BD worsen over time, patients confront with more severe body pain, mobility restrictions, and difficulties in chewing, eating, speaking and swallowing which negatively affect social interactions of patients and reduce their QOL. Furthermore, depression was proved to act as a deteriorating factor for HRQOL among BD patients. Thus, patients need to be psychologically supported by a specialized team and be informed during the course of treatment to gain useful information about the disease, treatment approaches and coping strategies.
Keywords :
HRQOL , Health-related quality of life , Behcet’s disease , Old Silk Route disease
