Author/Authors :
Farrokhi, Mehrdad Eris Research Institute, Tehran, Iran , Yarmohammadi, Bardia School of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mangouri, Amir Department of Vascular and Endovascular Surgery - Sina Hospital - Tehran University of Medical Sciences, Tehran, Iran , Hekmatnia, Yasaman Islamic Azad University Sari Branch, School of Medicine, Sari, Iran , Bahramvand, Yaser School of Medicine - Shiraz University of Medical Sciences, Shiraz, Iran , Kiani, Moein School of Medicine - Zanjan University of Medical Sciences, Zanjan, Iran , Nasrollahi, Elham School of Medicine - Shiraz University of Medical Sciences, Shiraz, Iran , Nazari-Sabet, Milad Department of General Surgery - School of Medicine - Isfahan University of Medical Sciences, Isfahan, Iran , Manoochehri-Arash, Niusha Endocrine Research Center, Research Institute for Endocrine Sciences - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Khurshid, Maria Department of Internal Medicine - Berkshire Medical Center, Massachusetts, USA , Mosalanejad, Shima Department of Internal Medicine - Faculty of Medicine - Islamic Azad University Tehran Medical Sciences Branch, Tehran, Iran , Hajizadeh, Vida School of Dentistry - Shiraz University of Medical Sciences, Shiraz, Iran , Amani-Beni, Reza School of Medicine - Isfahan University of Medical Sciences, Isfahan, Iran , Moallem, Masoumeh Department of Emergency Medicine - School of Medicine - Islamic Azad University Tehran Medical Sciences Branch, Tehran, Iran , Farahmandsadr, Maryam School of Medicine - Jahrom University of Medical Sciences, Jahrom, Iran
Abstract :
Introduction: Recent studies have suggested that point-of-care ultrasonography can be used for confirming the
placement of endotracheal tube. This systematic review and meta-analysis aimed to investigate the sensitivity
and specificity of ultrasonography for confirming endotracheal tube placement. Methods: In thismeta-analysis,
systematic search of the previous published papers investigating the diagnostic accuracy of ultrasonography for
confirmation of endotracheal tube placement was performed. Seven electronic databases, including PubMed,
Scopus, Google Scholar, EBSCO, EMBASE, Web of Science, and Cochrane Database were searched up to July
2021, for all relevant articles published in English on this topic. Meta-DiSc version 1.4 software was used for statistical
analysis. Results: The estimated pooled sensitivity and specificity of ultrasonography for confirmation of
endotracheal tube location were 0.98 (95% CI: 0.98–0.99) and 0.94 (95% CI 0.91–0.96), respectively. The pooled
positive likelihood ratio and negative likelihood ratio were 5.94 (95% CI 4.41–7.98) and 0.03 (95% CI: 0.02-0.04),
respectively. The diagnostic odds ratio of ultrasonography was 281.47 and the area under hierarchical summary
receiver operating characteristic (HSROC) revealed an appropriate accuracy of 0.98. Conclusion: Ultrasonography
has high diagnostic accuracy and can be used as a promising tool for confirmation of endotracheal tube
placement, especially in critically ill patients or when capnography is not available, or its result is equivocal.
