Title of article
Drug Reaction with Eosinophilia and Systemic Symptom in a Patient with Pneumonia and Hyperthyroidism
Author/Authors
Jin, Hualiang Department of Respiratory Diseases - Hangzhou First People’s Hospital - Nanjing Medical University - Hangzhou, Zhejiang, China , Wang, Limin Department of Respiratory Diseases - Hangzhou First People’s Hospital - Nanjing Medical University - Hangzhou, Zhejiang, China , Ye, Jian Department of Respiratory Diseases - Hangzhou First People’s Hospital - Nanjing Medical University - Hangzhou, Zhejiang, China
Pages
4
From page
130
To page
133
Abstract
Drug rash with eosinophilia and systemic symptoms syndrome is an idiosyncratic drug reaction characterized by fever, skin eruption, lymph node enlargement, and internal organ involvement. We report a case of a patient with pneumonia who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (renal failure and eosinophilic pneumonitis) caused by methimazole. The patient improved remarkably with drug withdrawal. A high index of clinical suspicion is emphasized to facilitate prompt diagnosis of medication-related adverse effect and its discontinuation.
Keywords
Drug rash with eosinophilia and systemic symptoms , hyperthyroidism , pneumonia , Methimazole
Journal title
Journal of Research in Pharmacy Practice
Serial Year
2017
Record number
2730946
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