Title of article :
The Antibacterial Characteristics of Fluorescent Carbon Nanoparticles Modified Silicone Denture Soft Liner
Author/Authors :
Obaid Aldulaim, Ahmed Kareem Department of Pharmacy - Al-Zahrawi University College, Karbala, Iraq , Hameed, Noora M Anesthesia techniques - Al–Nisour University College, Iraq , Ahmed Hamza, Thulfeqar Medical laboratory techniques department - Al-Mustaqbal University College, Babylon, Iraq , Abed, Ahmed S Department of Prosthetic Dental Technology - Hilla University college - Babylon, Iraq
Abstract :
Opportunistic oral fungal infections have become more common despite advancements in treatment, particularly in people who wear dentures. The most logical explanation of this infectious disease’s beginning is a confluence of yeast cells becoming stuck in irregularities in denture-relining and denture-base materials, poor oral hygiene, and a number of systemic variables. The growth and colonization of microorganisms are potential downsides of prolonged usage of soft liners. Clinical issues and material damage may emerge from Candida albicans (C. albicans) and Staphylococcus aureus (S. aureus) colonizing soft lining materials. The purpose of this study was to determine how adding fluorescent carbon nanoparticles (FCNPs) to a denture soft liner affected that liner’s capacity to prevent bacteria growth. From a soft denture liner, 48 samples were collected and divided into a test group and a control group, each of which received 5% by weight of FCNPs. Antimicrobial tests were performed on C. albicans, S. aureus, and a combination of biofilms. Prior to and following six months of storage in distilled water, results on the cell density count and adhesion assay were gathered. The findings demonstrated that the modified group’s antibacterial activity was significantly higher than that of the control group. Additionally, both before and after the storage period, the addition of 5% nanofiller considerably decreased the growth of C. albicans, S. aureus, and the biofilm mixture (P<0.05). Adding 5% by weight of FCNPs to the denture soft liner for up to six months significantly prevented the growth of C. albicans and S. aureus.
Keywords :
Candida albicans , Microbial colonization , Nanoparticle , Soft liner
Journal title :
Journal of NanoStructures