Application of Polymer Supported Base in Solid Phase Synthesis: Convenient Synthesis of N-Aryl-N-benzyl Piperazine Derivatives

N-Aryl-Nʹ-benzyl piperazine derivatives were synthesized using REM resin. In cleavage step, the piperazine derivatives were successfully prepared in a good yield and excellent purity by treatment with novel polymer supported base in the absence of any base.