Preparation and Characterization of New Hetrocyclic Azo Thiozal Dye Ligand and Its Use as a Reagent for Determination of Zn+2 Ion in Drug by New Analytical Method

A novel heterocyclic organic ligand was synthesized by using a novel azo reagent and characterized by the organic diagnostic methods such as FT-IR, 1H-NMR, and UV-Vis. The novel azo reagent was employed in the analytical approach to find trace levels of zinc(II) ion in several drug models. The complex was formed after studying the optimal conditions for its synthesis in a reagent: zn+2 ratio of 1:1. The largest absorption peak was seen at 620 nm in wavelength. In contrast, the reagent wavelength was 475 nm. The linear range was between concentration and absorption at longer wavelength ranges 0.3 - 20 mg/L. The approach has an accuracy of percent RSD 0.9259 and SD =0.0005. Sandal sensitivity, LOD, and LOQ are each 0.2632, 0.8772 g/mL, and 0.1754 g.cm-2, respectively. The impact of various positive and negative ions on complex absorption was examined to demonstrate the method s selectivity. Under the optimal pH 6.5 to 7 conditions and an absorption temperature of 25 to 40 °C, the percentage recovery of the drug by the suggested method varied from 95 to 104 %.