Highly Anomer- and Regio-selective Transesterification Catalyzed by Alkaline Protease from Bacillus subtilis in Organic Media

Highly anomer-selective-6(6ʹ)-acylation reactions from anomeric mixtures of several mono- and disaccharides with divinyl dicarboxylates ranging from 4 to 10 carbon atoms were catalyzed by an alkaline protease from Bacillus subtilis in pyridine. A series of new pure (alpha)-anomeric polymerisable vinyl sugar esters of dibasic acids were synthesized in good selectivity and yields.