Title of article :
Synthesis and diagnosis of triazole and oxirane derivatives from hydroxyquioline with evaluating their biological and antioxidant activity
Author/Authors :
Shkyair Lihumis ، Hala Department of Chemistry - Faculty of Science - University Babylon , Sami Abd ، Abbas Department of Chemistry - Faculty of Science - University Babylon , Sadiq Mahdi Al-khateeb ، Dalia Department of Genetic Engineering - Faculty of Biotechnology - AL-Qasim Green University Iraq , A. Mubarak ، Hayfaa Department of Chemical Engineering - Faculty of Engineering - University Babylon , M. Karhib ، Mustafa Department of Medical Laboratory Techniques - Al-Mustaqbal University College , Mousa Kareem ، Mohanad Department of Chemistry - Faculty of Science - University Babylon , Abdullah Aowda ، Saadon Department of Chemistry - Faculty of Science - University Babylon
Abstract :
Research involved preparing new compounds from hydroxyquioline with formaldehyde to form P1 and then reacted with benzylalcohol to form P2 reacted chloroaceticacid and SOCl2 to form P3 and P4 with thiosemicarbazide to form P5 and P2 reacted with benzydehyde to form chalcone reacted with H2O2 to form P8. The compounds were identified via TLC, FTIR 1HNMR and 13CNMR. The measured the antibacterial and antioxidant activity of the prepared compounds, to give high resulte.
Keywords :
hydroxyquioline , benzylalcohol , Formaldehyde , Thiosemicarbazide , benzydehyde antioxidant , Biological activity
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
