Title of article :
Subependymal giant cell astrocytoma, report of a rare case
Author/Authors :
Darvishi ، Behnaz Students Research Committee,Clinical Research Development Center, Imam Reza Hospital Center, Imam Reza Hospital - Kermanshah University of Medical Sciences , Farhad ، Negin Students Research Committee,Clinical Research Development Center, Imam Reza Hospital , Ramezani ، Mazaher Imam Reza Hospital,Molecular Pathology Research Center,Clinical Research Development Center - Kermanshah University of Medical Sciences
Abstract :
Tuberous sclerosis complex (TSC) is a rare genetic disease that is inherited autosomal dominantly and may be associated with subependymal giant cell astrocytoma (SEGA) in 10-20% of cases. Different phenotypes are related to the form of lesions in different parts of the body, including skin, brain, kidneys, lungs, and heart. Age of patient, location of the tumor, and associated skin or neurological lesions may guide the pathologist for a definite diagnosis. Here we report a case of SEGA in an adolescent with TSC. Neurological clues including seizure and mental retardation, facial angiofibroma, renal mass, and histopathology examination of brain tumor culminated in the diagnosis of TSC and SEGA.
Keywords :
Subependymal giant cell astrocytoma , Tuberous sclerosis complex
Journal title :
Basic and Clinical Cancer Research
Journal title :
Basic and Clinical Cancer Research
