Determining the Correlates of Quality of Life (QoL) in the Elderly with Chemotherapy-Induced Neuropathy in Cancer Patients: a Multimodal Systematic Review

Introduction: Since neuropathy caused by chemotherapy is associated with a very high prevalence in the elderly and this issue can have adverse effects on the QoL of these people, and considering that there are different results regarding the extent of the effects of neuropathy caused by chemotherapy There is an effect on the QoL of the elderly. In this multifaceted systematic review, we decided to obtain the relationship between the QoL in the elderly with neuropathy caused by chemotherapy in cancer patients and reach a final conclusion. Methodology: The current study was a multifaceted systematic review; This study was conducted during the last quarter of 2022 in Tabriz University of Medical Sciences; All electronic databases that published articles related to cancer, QoL, neuropathy, chemotherapy and the elderly were searched for the purposes of this research. Results: The QoL of the elderly had a statistically significant relationship with gender and co-morbidities, so that the QoL score in men and also the elderly without co-morbidities was significantly higher than other elderly; Also, the average QoL in the elderly with a disease duration of less than one year was significantly higher than that of the elderly with a disease duration of more than 5 years. Conclusion: This study showed that the QoL in a high percentage of elderly people with chemotherapy-induced neuropathy was favorable, which can be related to many factors. Considering that the highest percentage of the research units were young elderly people (age between 60 and 74 years old) and married people who have higher functional capacities and physical abilities than old or very old elderly people and probably benefit from more family and social support. They are far from the adverse psychological consequences that are reported in research for single and single elderly people.