Adenosquamous Carcinoma of the Colon: A Report of Two Cases and Literature Review

Colon cancer is one of the commonest tumours in the world. Although most colon cancer patients are colonized by adenocarcinoma, some other pathologies such as adenosquamous carcinoma are rarely encountered. We present two patients with right colon adenosquamous carcinoma. Both patients were males and both suffered a nodepositive disease. Furthermore, one of them developed recurrence 7 months after initial radical surgery, despite formal colon adjuvant chemotherapy given. In conclusion, the patients with adenosquamous colon cancer are a subgroup with a worse prognosis, and questionable response to the conventional chemotherapeutic regimens as FOLFOX (flourouracil, leucoverin, and oxaloplatin) and CAPEOX (capecitabine and oxaloplatin).