Title of article :
The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology
Author/Authors :
Zarei ، Reza Department of Statistics - Faculty of Mathematical Sciences - University of Guilan , Mirmasoudi ، Sahra Burn and Regenerative Medicine Research center - Guilan University of Medical Sciences , Feizkhah ، Alireza Department of Medical Physics - School of Medicine - Guilan University of Medical Sciences , Pourmohammadi Bejarpasi ، Zahra Burn and Regenerative Medicine Research center - Guilan University of Medical Sciences , Shahrousvand ، Mohsen Caspian Faculty of Engineering, College of Engineering - University of Tehran
Abstract :
This study focuses on optimizing process of the blood coagulation powder composition with response surface methodology. For this purpose, optimizing the synthesis conditions of powder composition, the response surface methodology (RSM) was used by Box-Behnken design (BBD). The variables of this method were sodium alginate (A) and zinc oxide nanoparticles (B), prepared in combination with a fixed percentage of shell powder and measured for different reactions. results showed that according to the response surface methodology, which is the most optimal case, to introduce this method as a suitable suggestion for this kind of problem in the applications of vascular surgeries, burns, etc., and direct to future pre-clinic and clinical studies.
Keywords :
RSM , Coagulation powder , Box , Behnken design
Journal title :
Computational Sciences and Engineering
Journal title :
Computational Sciences and Engineering
