Title of article
The Connection between Platelets and the Development of Cancer
Author/Authors
Zamanian ، Golnaz Experimental Medicine Research Center - Tehran University of Medical Sciences , Ghoraishizadeh ، Peyman Department of Clinical Microscopy - Faculty of Medical Technology - Mahidol University , Hossein Bazrafshani ، Sajad E.N.T. Department - Worcester Royal Hospital
From page
36
To page
42
Abstract
Platelets are tiny (2-4 m), anucleate, hematopoietic cells that are discharged into the circulation by bone marrow megakaryocytes. Platelets were formerly thought to be the main agents of hemostasis and thrombosis. Armand Trousseau established a strong link between thrombosis and cancer in 1865. The hypothesis that platelets play many roles in the development of malignancies and in cancer-associated thrombosis is thus supported by a wealth of clinical and experimental data.The functions of tumor-educated platelets (TEPs) in the development of cancer, from primary tumors to subsequent metastatic breakouts, will be covered in this study.
Keywords
Cancer , Tumor , Metastatic , Platelets
Journal title
Personalized Medicine Journal
Journal title
Personalized Medicine Journal
Record number
2743112
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