Clinical and Pathological Features of Iraqi Patients with Prostate Cancer

Background: The clinical pathological features were detected by measuring the prostatic acid phosphatase (PAP) activity according to the stages and grades of prostate cancer. We also explored the relationship between the disease and age with family history among the patients. Methods: Data were collected from direct interview and from the patient’s records. Blood samples that collected before the surgery from Baghdad hospitals. By using the ELISA device, PAP enzyme activity was determinred using Automated Chemiluminescent Immunometric Assay. Result: Older individuals were more likely to develop prostate cancer since out of the 50 samples collected, most (46%) were ≥60 years old. 23 (46%) cases were in stage II of PCa and 29 (58%) had grade-II as the most dominant stage and grade. Family history from parents to sons had a significant role in the possibility of being positive for prostate cancer. A positive family history was found in 72% of the cases of PCa, and it was found that the enzymatic activity of the PAP enzyme rises in the presence of prostate cancer. Conclusion: PAP enzyme is reliable in diagnosing the presence of prostate cancer, as the increase in the activity of the enzyme PAP coincides with the presence of prostate cancer.