Title of article :
Review of Molecular Approaches in Leishmaniasis Vaccines: Implications and Restrictions
Author/Authors :
Fattahi Bafghi ، Ail Department of Parasitology and Mycology - Infectious Diseases Research Center, School of Medicine - Shahid Sadoughi University of Medical Sciences , Rezaee ، Elham Parasitology Department - Paramedical School - Gerash University of Medical Sciences , Ahmadi ، Somayeh Department of Parasitology and Mycology - School of Medicine - Shahid Sadoughi University of Medical Sciences , Gholamrezaei ، Mostafa Department of Parasitology and Mycology - School of Medicine - Shahid Sadoughi University of Medical Sciences , Firouzeh ، Nima Vector-Borne Diseases Research Center - North Khorasan University of Medical Sciences
Abstract :
Leishmaniasis, a cosmopolitan parasitic infection, is a sandfly-borne parasitic disease caused by di erent species of Leishmania. Many attempts have been made to discover e ective and safe vaccines against leishmaniasis, but most of them are not accompa-nied by promising results. During the last decade, the characterization of new antigens for potential vaccine candidates based on classical and molecular protocols has been a hot research topic in immunological science. The present review focuses on the devel-opment and the status of various vaccines and potential vaccine candidates against leishmaniasis. Here, molecular approaches to leishmaniasis vaccine development are described. Also, implications and restrictions are discussed.
Keywords :
Vaccine , Molecular , Leishmaniaspp. , Leishmaniasis
Journal title :
International Journal of Infection
Journal title :
International Journal of Infection
