Title of article :
Association of serum apelin and atherogenic indices in patients with primary thyroid diseases
Author/Authors :
Najim ، Murtadha K. Rifai General Hospital, Dhi Qar Health Directorate - Iraqi Ministry of Health , Lahhob ، Qais R. Rifai General Hospital, Dhi Qar Health Directorate - Iraqi Ministry of Health , Abbasd ، Hamid J. Al-Faiha Teaching Hospital, Al-Zahra’a Medical College - University of Basrah , Alidrisie ، Haider A. Faiha Specialized Diabetes, Endocrine and Metabolism Center, College of Medicine - University of Basrah , Ibrahimf ، Zahraa Jaber Qalat Sukkar Sector of Primary Health Care - Dhi Qar Health Directorate - Iraqi Ministry of Health , Budaiwig ، Zainab Kazem Shatrah General Hospital, Dhi Qar Health Directorate - Iraqi Ministry of Health , Abdul-Jabbarh ، Zainab Haider Al-Nasiriyah Sector One - 15th Sha ban Center, Dhi Qar Health Directorate - Iraqi Ministry of Health , Kadhami ، Mustafa Jawad Department of Forensic Sciences - College of Medical Techniques - Al-Farahidi University , Maatookj ، Majid A. Medical Laboratory Technology Dept. - College of Health and Medical Technology - Southern Technical University
Abstract :
Apelin is an adipocytokine secreted from adipocytes. Although much research has been conducted on apelin, no or few reports are there about its association with atherogenic indices in patients with thyroid dysfunctions. The aim of this study is to investigate the association between serum apelin and atherogenic indices. A total of 177 participants were included in the current study (43 controls and 124 patients with thyroid dysfunction). Serum apelin and lipid profile tests were determined and atherogenic indices were calculated for each participant. Higher concentrations of Apelin level in hyperthyroidism were compared with control groups and hypothyroidism. All types of an atherogenic indices indicated a significant increase in hypothyroidism more than hyperthyroidism and control groups, the atherogenic indices (AIP, CRI-I, CRI-II, AC, and Chol indices) had more diagnosis accuracy than apelin in a diagnosis of hypothyroidism group, despite of that apelin had more diagnosis accuracy than atherogenic indices (AIP, CRI-I, CRI-II, AC, and Chol indices) in a diagnosis of hyperthyroidism group. The apelin was significantly increased in hyperthyroidism compared with hypothyroidism.
Keywords :
atherogenic , hyperthyroidism , hypothyroidism diagnostic accuracy , dyslipidemia
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
