Title of article :
Ataxia-telangiectasia With Acute Rheumatic Fever: A Case Report
Author/Authors :
Khosravi ، Mohammad Reza Student Research Committee, School of Medicine - Mazandaran University of Medical Sciences , Abbasi ، Ghazal Student Research Committee, School of Medicine - Mazandaran University of Medical Sciences , Shahbaznejad ، Leila Pediatric Infectious Diseases Research Center, Communicable Diseases Institute - Mazandaran University of Medical Sciences , Ghaffari ، Javad Pediatric Infectious Diseases Research Center, Communicable Diseases Institute - Mazandaran University of Medical Sciences , Dabghzade ، Abbas Pediatric Infectious Diseases Research Center, Communicable Diseases Institute - Mazandaran University of Medical Sciences
Abstract :
Background: Ataxia-telangiectasia is a multi-organ disease. It is due to a mutation of the Exon No. 5 ataxia telangiectasia mutated gene (c.381delA: p.v128fls). Complications including recurrent infections, progressive cerebellar ataxia, and varying degrees of humoral and cellular immunodeficiency arise. Case Presentation: We report a 7-year-old girl patient with A-T who developed acute rheumatic fever. Conclusion: Rheumatoid disorders and or infectious diseases such as acute rheumatic fever could be observed in A-T patient.
Keywords :
Ataxia , telangiectasia , Mutation , Immunocompromised patient , Acute rheumatic fever
Journal title :
Journal of Pediatrics Review
Journal title :
Journal of Pediatrics Review
