Can physical activity affects on Omicron mutation: Cross talk between skeletal muscle and the immune system

Omicron, a new type of SARS-CoV-2 was first reported by South Africa to the World Health Organization (WHO) on November 24, 2021. Two days after Africa was reported to the World Health Organization, the Omicron was identified as a global threat. Omicron has many genetic mutations, the potential effects of which are more dangerous than other SARS-CoV-2 genetic mutations. With the increase in vaccination in the world, the amount of physical activity to improve the functioning of the immune system decreased. Relying on vaccines alone cannot guarantee an improvement in the functioning of the immune system and the people of the world, given the lack of knowledge about the prevalence of omicron and its potential dangers, should look for ways to boost the immune system. In this study, we highlight the importance of increasing physical activity at the time of omicron outbreaks, along with the proposed protocols.