Author/Authors :
hameed, b. kh. tikrit university - veterinary medicine faculty - department of anatomy and histology, Tikrit, Iraq , fadhil, r. m. tikrit university - veterinary medicine faculty - department of physiology, pharmacology and biochemistry, Tikrit, Iraq , hussain, rasha sh. tikrit university - faculty of education for pure science - department of biology, Tikrit, Iraq , abdullah, buthina a. tikrit university - veterinary medicine faculty - department of physiology, pharmacology and biochemistry, Tikrit, Iraq , hadi, kh. a. tikrit university - veterinary medicine faculty - department of physiology, pharmacology and biochemistry, Tikrit, Iraq , obid, wassan s. tikrit university - veterinary medicine faculty - department of physiology, pharmacology and biochemistry, Tikrit, Iraq , hadree, d. h. tikrit university - veterinary medicine faculty - department of physiology, pharmacology and biochemistry, Tikrit, iraq , gabori, enaam a. al-noor university college - department of medical laboratory technique, Mosul, Iraq , mustafa, nadya e. ministry of education - general directorate for education of kirkuk, Iraq
Abstract :
WE used in our study Twenty rats ,divided into two groups .the first group consist of 10 rats considered as a control group, while the second group treated with 0.05 mlbody weightday of dipyron injected for 30 days duration. The toxic effect of dipyrone was obvious in the different tissue and haematotoxic effects . The histological changes were obvious in the hepatic cell whichof liver were characterized by atrophy ,irregular hepatic cells ,RBC cells in the blood sinusoid. However,the spleen tissue contains nodule (white pulpe ).The bony tissue have osteocytes large bony vacuoles and the blood vessel were congested.