Author/Authors :
nafar, mohsen shahid beheshti university of medicalsciences - shahid labbafinejad medical center. chronic kidney disease research center (ckdrc),labbafinejad hospital - division of nephrology, department of internal medicine,labbafinejad hospital, Tehran, iran , ahmadpoor, pedram shahid beheshti university of medical sciences - shahid labbafinejad medical center. chronic kidney disease research center (ckdrc),labbafinejad hospital - division of nephrology, department of internal medicine,department of nephrology, Tehran, Iran , otaibi, torki al hamed al-essa organ transplant center - transplant nephrology department, Kuwait. , alotaibe, fahad e university of dammam - college of medicine,multi-organ transplant center, king fahad specialist hospital - department of internal medicine, Dammam, Saudi Arabia , albugami, meteb m university of dammam - multi-organ transplant center, king fahad specialist hospital,college of medicine - department of internal medicine, Dammam, Saudi Arabia , habhab6, wael university of baghdad - baghdad college of medicine, fellowship of the royal college of physicians, frcp london - baghdad college of medicine,university of baghdad., Baghdad, iraq , habhab6, wael king faisal specialist hospital and research centre - department of medicine, Jeddah, Saudi Arabia , dalili, nooshin shahid beheshti university of medical sciences, - shahid labbafinejad medical center, labbafinejad hospital , chronic kidney disease research center (ckdrc) - division of nephrology, department of internal medicine, department of nephrology, Tehran, Iran , glotz, denis university paris-diderot and inserm u1160 - hopital saint louis, France, Paris
Abstract :
Purpose: Delayed graft function (DGF) is a form of acute renal failure which results in increased post-transplantation allograft immunogenicity and risk of rejection episodes in addition to decreased long-term survival. Its incidence and risk factors have been extensively studied, especially after deceased donation. However until now, only few data has been published on DGF in living donor kidney transplant recipients. The present study was performed to investigate the frequency and risk factors of DGF among living- kidney transplant recipients.Material and Methods: In this retrospective study, 500 living kidney transplant recipients recruited and data collected from hospital registries in three countries (Iran, Kingdom of Saudi Arabia (KSA) , and Kuwait ).Results: Incidence of DGF revealed to be %95) %2.3 CI: %3.6-%0.9). DGF group showed significant older age for the recipients and in “without DGF” group, there were more females, and lower weight for the recipients. It was found that patients with DGF had longer pre transplant dialysis duration, cold ischemic and anastomosis time during surgery . Conclusion: DGF after living-donor kidney transplantation is a multifactorial complication which donor, recipient, and technical factors would lead toward. Consideration and optimization of these risk factors may drive through better long-term patient and graft outcomes in living kidney transplant recipients.
