Long-term Outcome of Synthetic Mesh Use in Iranian Women with Genital Prolapse

Purpose: To evaluate the long-term outcome of synthetic mesh use in the treatment of women with Pelvic organ prolapse (POP).Materials and Methods: We evaluated the outcome of synthetic mesh implantation by vaginal surgery method in 153 women (mean age of 9.31±53.66 years) with POP grade 2 in the anterior compartment. Demographic findings, baseline symptoms as well as subjective and objective outcome were recorded during the follow-up period of 11.33±36.89 months. Results: POP relapse occurred in %3.3 indicative of %96.7 anatomical success rate. Patients’ common baseline findings were frequency (%72.5), stress and urge incontinence (%59.5 and %47.7). Subjective outcome were vaginal pain (%13.7), dyspareunia (%9.2) and tension feeling (%8.5), while objective outcomes were mesh exposure (%3.9), urge incontinence (%11.1) and vaginal infection (%1.3). Stress incontinence was completely treated following surgery. There was significant improvement in dyspareunia, vaginal pain, urge and stress incontinence (all p 0.001) and fecal incontinence (p = 0.02). After surgery, %88.42 were satisfied of the surgery outcome. Conclusion: POP surgery with synthetic mesh has acceptable results, considerable improvement in symptoms and high rate of satisfaction during follow-up; however, side effects are not uncommon but tolerable