Analyze Digital Images by Improving the Methods of Advanced Intelligence by the Image Processing Program Developing Process

The remarkable development of digital photography has been possible thanks to joint ad-vances in computer science and photography processing and retouching software. The scien-tific use of photography is now possible as long as its intrinsic limits are comprehended, par-ticularly in the very specific time-limited structure of clinical trials. We list the two main limi-tations inherent to this method: geometrical calibration and colorimetric calibration. These li-mitations are illustrated by numerous images used in our practice in Besancon during the last decade.