Author/Authors :
saffaei, ali shahid beheshti university of medical sciences - school of pharmacy - department of clinical pharmacy, tehran, iran , zahed, narges sadat shahid beheshti university - loghman-hakim hospital - department of nephrology, tehran, iran , shadnia, shahin shahid beheshti university of medical sciences - toxicology research center , loghman hakim hospital - department of clinical toxicology, tehran, iran , erfan talab evini, peyman shahid beheshti university of medical sciences - toxicological research center, loghman hakim hospital - department of clinical toxicology,, tehran, iran , rahimi, mitra shahid beheshti university of medical sciences - toxicological research center,loghman hakim hospital - department of clinical toxicology, tehran, iran (islamic republic of)
Abstract :
introduction: aluminum phosphide (alp) is an effective fumigant and rodenticide which is a commonly used agent for suicide in parts of developing countries. alp poisoning results in serious manifestations involving many vital organs and it has high mortality. electrolyte and metabolic abnormalities including metabolic acidosis is a common problem in alp poisoning. case report: here, we report two cases of alp poisoning who take alp tablets intentionally. the therapeutic intervention initiated for both of them including glucose, insulin, and potassium (gik) protocol, antioxidants agents, intravenous magnesium, intravenous calcium, and norepinephrine. the arterial blood samples obtained in a serial manner and interestingly it showed no abnormality.conclusion: this is first cases of alp poisoning with normal acid base balance which emphasis the importance the early initiation of therapeutic intervention
Keywords :
aluminum phosphide , acidosis , poisoning , toxicity , blood gas
