Title of article :
Investigating Bisphenol A Level Estimation and Possible Effects on Fetal Biometry
Author/Authors :
Elbendary ، Reham Nafad Forensic Medicine and Clinical Toxicology, Faculty of Medicine - Cairo University , Attia ، Abla Abdel Meguid Forensic Medicine and Clinical Toxicology, Faculty of Medicine - Cairo University , Zakaria ، Mohamed Ahmed Yehia Forensic Medicine and Clinical Toxicology, Faculty of Medicine - October 6 University , Sakr ، Sakr Mohammed Forensic Medicine and Clinical Toxicology, Faculty of Medicine - October 6 University , Haggag ، Hisham Mamdouh Hamed Department of Obstetrics Gynecology - Faculty of Medicine - Cairo University , Taha ، Sara Hamed N Forensic Medicine and Clinical Toxicology, Faculty of Medicine - Cairo University , Saeed Mohammed ، Howaida Forensic Medicine and Clinical Toxicology, Faculty of Medicine - Cairo University
Abstract :
Background: The estrogenic endocrine disruptor bisphenol A (BPA), which is used in plastics and resins, may have an impact on the fetus’s growth and development and can modify postnatal development. This study aims to assess how bisphenol A affects fetal biometry. Methods: This analytical cross-sectional study included 384 healthy Egyptian women in their third trimester during childbearing (15–44 years). They were selected from the outpatient Clinic of Obstetrics and Gynecology at Kasr El-Ainy Hospital, Cairo, Egypt. Fetal biometry was measured and urine samples were collected to estimate BPA levels. Results: Fetal weight, centile, and corrected bisphenol A levels were significantly higher in the studied age groups (P 0.05). A significant positive correlation was found between BPA level and estimated fetal weight, centile, and age of the mother per year. On the other hand, no significant difference was detected with other fetal measurements in the studied groups (P 0.05). Conclusion: Fetal exposure to BPA is associated with higher estimated fetal weight and centile commonly in the maternal age range 25 to 35 years.
Keywords :
Bisphenol AEndocrine , disruptingFetal biometryGrowth , Egypt
Journal title :
International Journal of Medical Toxicology and Forensic Medicine
Journal title :
International Journal of Medical Toxicology and Forensic Medicine