Title of article :
Combined Treatment of Progressive Encephalitis in an X-linked Agammaglobulinemia Patient
Author/Authors :
Yamazaki-Nakashimada ، Marco Department of Pediatric Clinical Immunology - Instituto Nacional de Pediatria , Herrera-Mora ، Patricia Department of Pediatric Neurology - Instituto Nacional de Pediatria , Mahrx-Bracho ، Alfonso Department of Pediatric Neurosurgery - Instituto Nacional de Pediatria , López-Herrera ، Gabriela Immunodeficiencies Research Unit - Instituto Nacional de Pediatria , Bustamante-Ogando ، Juan Immunodeficiencies Research Unit - Instituto Nacional de Pediatria , Scheffler-Mendoza ، Selma Department of Pediatric Clinical Immunology - Instituto Nacional de Pediatria
Abstract :
Most patients with X-linked agammaglobulinemia are susceptible to infections, while some cases also suffer from inflammatory or autoimmune complications. We describe a patient with progressive encephalitis who improved after the use of immunomodulatory treatment with corticosteroids, fluoxetine, and nitazoxanide. In most of the cases the evolution of the progressive encephalitis is complicated and catastrophic. Based on our experience and the review of the literature, we propose the use of this combined treatment to control this devastating complication.
Keywords :
Agammaglobulinemia , Immunomodulators , Primary immunodeficiency diseases , Neuroinflammatory diseases , Therapy
Journal title :
Iranian Journal of Allergy, Asthma and Immunology
Journal title :
Iranian Journal of Allergy, Asthma and Immunology