Title of article
Seroprevalence of Herpes Simplex Viruses Types 1 and 2 in a Population, Age 15-35 Years, of Mashhad City
Author/Authors
Taherpoor ، Ahmad Department of Microbiology and Virology - Faculty of Medicine - Mashhad University of Medical Sciences , Vojdani ، Arastoo Department of Microbiology and Virology - Faculty of Medicine - Mashhad University of Medical Sciences , Hashemi ، Mohamad Ali Student Research Committee, Faculty of Medicine - Mashhad University of Medical Sciences , Amali ، Arian Paramedical Department - Student Research Committee - Islamic Azad University, Mashhad Medical Sciences Branch , Mardani ، Mohammad Reza Department of Microbiology and Virology - Faculty of Medicine - Mashhad University of Medical Sciences , Mobarhan ، Majid Ghayour Department of Nutrition - International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, School of Medicine - Mashhad University of Medical Sciences , Esmaily ، Habibollah Social Determinants of Health Research Center - Mashhad University of Medical Sciences , Shakeri ، MohammadTaghi Social Determinants of Health Research Center - Mashhad University of Medical Sciences , Bakhshi ، Mansoureh Antimicrobial Resistance Research Center - Mashhad University of Medical Sciences , Meshkat ، Mojtaba Department of Community Medicine - Faculty of Medicine - Islamic Azad University, Mashhad Medical Sciences , Hooshyar Chechaklou ، Amin Antimicrobial Resistance Research Center - Mashhad University of Medical Sciences , Abolbashari ، Samaneh Antimicrobial Resistance Research Center - Mashhad University of Medical Sciences , Gholoubi ، Aida Metabolic Syndrome Research Center and Medical Genetics Research Center - Mashhad University of Medical Sciences , Meshkat ، Zahra Antimicrobial Resistance Research Center - Mashhad University of Medical Sciences
From page
152
To page
157
Abstract
Background: Considering the high prevalence and clinical importance of herpes simplex virus (HSV) infection worldwide, we aimed to evaluate the seroprevalence of HSV-1 and HSV-2 in a population aged between 15 and 35 years in Mashhad, Iran. Methods: This cross-sectional study was conducted on 916 cases composed of 288 (31.4%) men and 628 (68.6%) women. Using ELISA method, the presence of IgM and IgG antibodies against HSV-1 and HSV-2 was assessed. Results: Among the population studied, 681 (74.3%) cases were positive for anti-HSV antibodies, while 235 (25.7%) cases were negative. Moreover, no IgMs were found and all positive subjects had IgG antibodies. Age (p 0.001), occupation (p 0.001), education (p = 0.006), smoking (p = 0.029), and BMI (p = 0.004) demonstrated a significant association with HSV-1 and HSV-2 infection. Conclusion: Our study indicates a high seroprevalence of HSV infection; however, there was no cases positive for IgM antibodies, suggesting the high prevalence of latent infection.
Keywords
Herpes Simplex Virus Type 1 , Herpes Simplex Virus Type 2 , Iran , Seroepidemiology
Journal title
Iranian Biomedical Journal(IBJ)
Journal title
Iranian Biomedical Journal(IBJ)
Record number
2761328
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