Synthesis of Aliphatic Polyester by Insertion of Glycols into Polyanhydrides Using Lipase Catalyst

Polyester synthesis was carried out by insertion-dehydration of glycols into polyanhydrides using Candida antarctica lipase as catalyst. The insertion of 1,8-octanediol into poly(azelaic anhydride) took place under mild reaction conditions to give the corresponding polyester with molecular weight of several thousands.