Title of article :
Effects of K5SiW11O39Co on Mitogenic Activity of Basic Fibroblast Growth Factor
Author/Authors :
Sun، Liwei نويسنده , , Wu، Qiang نويسنده , , Liu، Ning نويسنده , , Yang، Cheng نويسنده , , Liu، Liyan نويسنده , , Liu، Zhiqiang نويسنده , , Zhao، Daqing نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
The interaction between polyoxometalate (POM) of Keggin class (K5SiW11O39Co) and human basic fibroblast growth factor (bFGF) was studied by fluorescence and CD spectra. The results indicate that the binding of POM to bFGF causes conformational changes of bFGF. The cell proliferation assay showed that in lower molar ratios, POM stimulates mitogenic activity of bFGF; in higher molar ratios, POM inhibits the mitogenic activity of bFGF.
Keywords :
Power requirement , Application-production research , Genetic-fuzzy system , prediction , Surface finish , grinding
Journal title :
CHEMISTRY LETTERS
Journal title :
CHEMISTRY LETTERS
