Assessment of Hypertension Effect on the Stone Formation in Different Section of Kidney

Introduction: According to the effect of hypertension on kidney stone formation and on the other hand, there is no research to evaluate the impact of hypertension on the location of stone formation in kidney, so the aim of present study was assessing the effect of hypertension on the location of stone formation in kidney.Methods: Data for present investigation were prepared by Persian Registry for Stones of Urinary System (PERSUS). This investigation was retrospective cohort and the study initially enrolled 5130 participants from 2020 to 2024. Participants with history of hypertension were selected and categorized as exposure group (n= 396). Participants without medical history and norm-tension were categorized as non-exposure group (n=396). Diagnosis of kidney stone was approved by CT-scan and data of medical history were collected by interview with patients.Results: The mean age of participants was 48.83±13.62 years. The distribution of kidney stone location was not significantly difference between two groups (P-value=0.1). The number of kidney stones in left and right kidney were not difference between patients with hypertension history and patients with norm-tension history (P-value=0.72, P-value=0.25).  There were no significant differences in stone formation in various parts of kidney between participants with hypertension and norm-tension history (P-value=0.16). Conclusion: Hypertension increased the risk of kidney stone formation but did not affect the location of stone formation in kidney.