A Comprehensive Review of Solvent-Induced Variability in Antioxidant Profiling of Plants Extract: Justicia secunda

Variability in antioxidant profiles, particularly within plant extracts like Justicia secunda and other plant extracts, presents a significant challenge for researchers striving to attain consistent and dependable outcomes in the realm of antioxidant profiling. This variability is predominantly attributed to the choice of solvents used during the extraction process. Our study delves deeply into the impact of solvent selection in the extraction process, revealing notable discrepancies in the antioxidant profiles of these plant extracts. This variation becomes evident through the diverse antioxidant potential observed across different solvents, emphasizing the pressing need for standardized methodologies to ensure research uniformity and reliability. Our review further explores the intricate interplay of diverse solvents employed during extraction procedures and their potential to induce variations in antioxidant profiles. It meticulously highlights the discernible fluctuations in antioxidant potential resulting from the use of different solvents, underscoring the imperative need for a systematic approach to research methodologies to guarantee consistent outcomes. The review concludes by presenting a forward-looking research agenda, including a comprehensive effort to identify and analyze specific antioxidant compounds within these extracts under various solvent conditions. Ultimately, our research seeks to enrich our understanding of the antioxidant properties and potential benefits associated with Justicia secunda. This review serves as an invaluable resource for researchers operating within this domain, spotlighting the pivotal role of solvent selection in antioxidant profiling and championing the cause of standardized methodologies to propel our knowledge forward in this area.