TRX Training Impact on Femur Neck Bone Density and Serum Leptin in Osteopenic Women: A Four-Month Study

Introduction: Osteoporosis, characterized by diminished bone mass and increased fracture susceptibility, prompts the investigation into the impact of a four-month TRX training regimen on femur neck bone mineral density (BMD) and its correlation with serum leptin levels in women with osteopenia. Material Methods: In this quasi-experimental study, 30 women with osteopenia were purposefully selected and randomly assigned to TRX training (n = 15) or control (n = 15) groups. The intervention group underwent TRX exercises thrice weekly for 45-60 minutes per session for four months. Blood samples collected at baseline and post-intervention measured serum leptin levels via ELISA kit (Bio vendor, Czech Republic), while Dexa Lexxos Digital (2D model, USA) determined femur neck BMD. SPSS 20 software, dependent/independent samples t-tests, and Pearson correlation were used for data analysis. Results: TRX training significantly increased femur neck BMD, reducing serum adiponectin levels versus the control group (P = 0.001 and P = 0.01, respectively). Compared to baseline, TRX training raised femur neck BMD and lowered serum leptin levels (P = 0.000 and P = 0.01, respectively). A significant inverse correlation emerged between femoral neck BMD and serum leptin levels in women with osteopenia (P = 0.00). Conclusion: Findings suggest that TRX resistance training holds promise for enhancing the rehabilitation of women with osteopenia