• Title of article

    Phytochemical and Antimicrobial Activities of Plant Extract (Morinda Lucida) on Phytopathogenic Fungal Isolates

  • Author/Authors

    Oladoyin ، Alabi Faculty of Science - Precious Cornerstone University , Omiyale ، Olumakinde Charles Faculty of Basic Medical Sciences - University of Lagos , Babalola ، Gbenga Jonathan Faculty of Clinical sciences - University of Lagos , Musa ، Adnan Faculty of Public Health and Healthcare - First Moscow State University-Sechenov University , Ojo ، Deborah Adepeju Faculty of Science - Lagos State University , Oduwe ، Ugochukwu Medical Laboratory Science - Faculty of Allied Health Sciences - Benson Idahosa University , Amaugo ، Love Chinyere Faculty of Medicine - Imo State University , Malgwi ، James Hamman Faculty of Pharmacy - General Hospital Biu , Olowofela ، Ifeoluwa Nursing Science Department - Babcock University

  • From page
    371
  • To page
    388
  • Abstract
    Morinda lucida, known as the Brimstone tree in Nigeria, is valued for its medicinal and agricultural uses in West Africa. This study investigates the antifungal properties of methanolic extracts from Morinda lucida against common fungal pathogens. Fresh leaves were collected from Ogbomosho, Oyo state, Nigeria, authenticated, and processed into powder. Methanolic extraction yielded a crude extract, which underwent phytochemical screening, revealing various bioactive compounds. The antifungal activity was evaluated against fungi like Aspergillus flavus and Rhizopus oryzae, showing significant inhibitory effects comparable to Nystatin. Minimum inhibitory concentration (MIC) was determined for each strain, highlighting broad-spectrum efficacy, particularly against Trichoderma harzianum. A pathogenicity test on oranges confirmed the extract’s ability to inhibit fungal growth. This study contributes to research on natural antifungal agents, supporting Morinda lucida’s traditional use in agriculture and healthcare. The extract shows promise for further development, pending studies on its mechanism, safety, and applications.
  • Keywords
    Morinda lucida , Antifungal activity , methanolic extract , Phytochemical analysis , Phytopathogenic fungi , Plant extract
  • Journal title
    International Journal of Advanced Biological and Biomedical Research (IJABBR)
  • Journal title
    International Journal of Advanced Biological and Biomedical Research (IJABBR)
  • Record number

    2769922